|
KMID : 0358419790220010035
|
|
Korean Journal of Obstetrics and Gynecology
1979 Volume.22 No. 1 p.35 ~ p.40
|
|
|
Effect of Serum Prolactin Levels on the Serum Concentrations of FSH, LH and Estradiol during Early Puerperium
|
|
라건영/Rha KY
이진용/Lee JY
|
|
|
Abstract
|
|
|
|
To elucidate the role of prolactin on the function of hypothalamic pituitaryovarian axis during the puerperium, concentrations of FSH, LH, prolactin and estradiol were measured in the sera of 8 lactating women and 7 women treated with bromocriptine. In the bromocriptine treated group serum mean prolactin level fell rapidly to 34ng/ml by the postpartum 3rd dary in association with the effective suppression of lactation, whereas the sustained high mean prolactin level of 247ng/ml on the postpartum 14th day in the lactating group. Serum FSH was barely detectable until the postpartum 5th day with increase back to 3-4mIU/ml on the postpartum 7th day in the lactating and bromocriptine treated groups. There was no significant difference in the concentration of FSH between both groups until the postpartum 14th day. Serum LH levels were higher than those of the normal menstrual cycle in both groups until the postpartum 14 days, probably due to contamination with remaining chorionic gonadotropin. Following clearance of placental estradiol during the post postpartum 7 days serum estradiol levels in the bromocription treated group rose again to 253 pg/ml at postpartum day 14, whereas those in the lactating group were remained low until the postpartum 14th day. In conclusion, it is suggested that the ovaries are the more refractory part of the hypothalamic-pituitary-ovarian axis during the postpartum period, due probably to the inhibiting role of prolactin on the ovarian steroidogenesis.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|
|